Pan African Analysis Identifies Genetic Differences in Prostate Cancer Risk
Abstract Men of African descent have the highest prostate cancer incidence and mortality rates, yet the genetic basis of prostate cancer...
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Sep 111 min read
The South African Prostate Cancer Screening Guidelines
Prostate cancer (PCa) is the most widespread solid organ malignancy in males and ranks as the fifth leading cause of death globally....
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Jul 20, 20231 min read
Using Population Descriptors in Genetics and Genomics Research: A New Framework for an Evolving...
Using Population Descriptors in Genetics and Genomics Research: A New Framework for an Evolving Field (2023). Contributors Committee on...
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Mar 13, 20231 min read
Testing the generalizability of ancestry-specific polygenic risk scores to predict prostate...
On behalf of NCI’s Epidemiology and Genomics Research Program (EGRP), it is my pleasure to inform you that your manuscript, Testing the...
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Dec 23, 20212 min read
A Rare Germline HOXB13 Variant Contributes to Risk of ProstateCancer in Men of African Ancestry
Burcu F. Darst , Raymond Hughley, Aaron Pfennig, Ujani Hazra, Caoqi Fan, Peggy Wan, Xin Sheng, Lucy Xia, Caroline Andrews, Fei Chen,...
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Sep 9, 20212 min read
Clinical Characteristics of PCa Patients in West and South Africa in the MADCAP Consortium
Mohamed Jalloh, Denzel Zhu, Ilir Agalliu, Caroline Andrews, Evan Kovac, Ben Adusei, Nana Yaa F. Snyper, James E. Mensah, Victoria Okyne,...
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Jun 3, 20211 min read
The rising burden of cancer in low- and middle-Human Development Index countries
Temidayo Fadelu, Timothy R Rebbeck First published: 04 June 2021 Abstract Cancer and other noncommunicable diseases represent a growing...
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May 15, 20211 min read
NIH Center for Global Health
Strategic Plan 2021-2025 Executive Summary The Center for Global Health (CGH) at the US National Cancer Institute (NCI) was established...
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Apr 5, 20211 min read
A tutorial on conducting genome-wide association studies: Quality control and statistical analysis
Andries T Marees, Hilde de Kluiver, Sven Stringer, Florence Vorspan, Emmanuel Curis, Cynthia Marie-Claire, Eske M Derks Abstract...
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Apr 2, 20212 min read
Trends in mortality among Black and White men with prostate cancer in Massachusetts and Pennsylvania
Hari S Iyer, Scarlett L Gomez, Jarvis T Chen, Quoc-Dien Trinh, Timothy R Rebbeck PMID: 33798264 PMCID: PMC8249310 (available on...
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Feb 10, 20211 min read
Sequence three million genomes across Africa
Ambroise Wonkam COMMENT 10 FEBRUARY 2021 Capture the full scope of variation to improve health care, equity and medical research...
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Jan 14, 20211 min read
Low generalizability of polygenic scores in African populations due to genetic & environ. diversity
NEW RESULTS January 14, 2021 Lerato Majara, Allan Kalungi, Nastassja Koen, Heather Zar, Dan J. Stein, Eugene Kinyanda, Elizabeth G....
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Jan 13, 20211 min read
Improved Prognostic Stratification Using Circulating Tumor Cell Clusters in Patients with Metastatic
Chun Wang, Zhenchao Zhang, Weelic Chong, Rui Luo, Ronald E Myers, Jian Gu, Jianqing Lin, Qiang Wei, Bingshan Li, Timothy R Rebbeck,...
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Dec 14, 20202 min read
Prostate cancer age-standardised incidence increase between 2006 and 2016 in Gauteng Province...
N Cassim, A Ahmad, R Wadee, T R Rebbeck, D K Glencross, J A George PMID: 33404002 DOI: 10.7196/SAMJ.2020.v111i1.14850 Abstract...
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Dec 7, 20202 min read
Novel Transcriptomic Interactions Between Immune Content and Genomic Classifier Predict Lethal...
Kosj Yamoah, Shivanshu Awasthi, Brandon A Mahal, Shuang G Zhao, G Daniel Grass, Anders Berglund, Julieta Abraham-Miranda, Travis Gerke,...
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Nov 24, 20202 min read
Discovering novel driver mutations from pan-cancer analysis of mutational and gene expression...
Houriiyah Tegally, Kevin H Kensler, Zahra Mungloo-Dilmohamud, Anisah W Ghoorah, Timothy R Rebbeck, Shakuntala Baichoo Published: November...
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Nov 4, 20202 min read
Racial and Ethnic Variation in PSA Testing and Prostate Cancer Incidence Following the 2012 USPSTF..
Kevin H Kensler, Claire H Pernar, Brandon A Mahal, Paul L Nguyen, Quoc-Dien Trinh, Adam S Kibel, Timothy R Rebbeck Published:04 November...
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Nov 3, 20202 min read
TMPRSS2-ERG fusion impacts anterior tumor location in men with prostate cancer
Kosj Yamoah, Priti Lal 2, Shivanshu Awasthi, Arash O Naghavi, Robert J Rounbehler, Travis Gerke, Anders E Berglund, Julio M Pow-Sang,...
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Oct 8, 20202 min read
Comparative Genomics Reveals Distinct Immune-oncologic Pathways in African American Men with...
Shivanshu Awasthi, Anders Berglund, Julieta Abraham-Miranda, Robert J Rounbehler, Kevin Kensler, Amparo Serna, Adriana Vidal, Sungyong...
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Sep 9, 20203 min read
Racial Differences in Genomic Profiling of Prostate Cancer
Authors Mahal BA, Alshalalfa M, Kensler KH, Chowdhury-Paulino I, Kantoff P, Mucci LA, Schaeffer EM, Spratt D, Yamoah K, Nguyen PL,...
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Jul 13, 20201 min read
Handbook for Cancer Research in Africa
In 1899 the surgeon Roswell Park predicted that cancer would overtake the common infectious diseases of the time as a killer of...
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Jun 30, 20202 min read
A custom genotyping array reveals population-level heterogeneity for the genetic risks of PrCa
A custom genotyping array reveals population-level heterogeneity for the genetic risks of prostate cancer and other cancers in Africa...
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Apr 8, 20202 min read
The association between neighborhood greenness and incidence of lethal prostate cancer
The association between neighborhood greenness and incidence of lethal prostate cancer: A prospective cohort study Authors Iyer HS, James...
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Mar 5, 20202 min read
Computationally Derived Image Signature of Stromal Morphology Is Prognostic of PCa Recurrence...
Computationally Derived Image Signature of Stromal Morphology Is Prognostic of Prostate Cancer Recurrence Following Prostatectomy in...
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Feb 18, 20202 min read
Mortality and Hospitalization Risk Following Oral Androgen Signaling Inhibitors Among Men with PCa..
Mortality and Hospitalization Risk Following Oral Androgen Signaling Inhibitors Among Men with Advanced Prostate Cancer by Pre-existing...
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Feb 14, 20202 min read
Integrative comparison of the genomic and transcriptomic landscape between prostate cancer patients
Integrative comparison of the genomic and transcriptomic landscape between prostate cancer patients of predominantly African or European...
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